VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Our results therefore implicate SIP1 in the regulation of vimentin observed in the EMT associated with breast tumor cell migration, a pathway that may contribute to the metastatic progression of breast cancer. 16568083 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Since vimentin and laminin staining is widely used by pathologists for diagnostic purposes, thus demonstrating the robustness of their specific antibodies, the immunohistochemical evaluation of these two molecules could be used in identification of basal-like breast tumours in both sporadic/familial cases. 17105822 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE This is mainly supported by the significantly higher incidence of vimentin-expressing breast cancers compared to any other myoepithelial breast tumours and the fact that vimentin is already observed in ductal in situ components. 15906273 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Treatments of human non-tumorigenic mammary epithelial and breast tumor cells with Lidocaine or Tetracaine caused rapid collapse of vimentin filaments. 21069453 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group LHGDN Our results therefore implicate SIP1 in the regulation of vimentin observed in the EMT associated with breast tumor cell migration, a pathway that may contribute to the metastatic progression of breast cancer. 16568083 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro. 24014025 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 PosttranslationalModification group BEFREE We therefore quantified Vimentin DNA methylation using MALDI-TOF mass spectrometry in breast tumors and matched normal pairs in association with gene expression and survival in a hospital-based study of breast cancer patients. 23239149 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group CTD_human Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer. 27811057 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group LHGDN Transactivation of vimentin by beta-catenin in human breast cancer cells. 12750294 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 AlteredExpression group LHGDN Down-regulation of vimentin expression inhibits carcinoma cell migration and adhesion. 17585878 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.380 Biomarker group BEFREE Here, we show that human breast tumor biomarker miR-30c regulates invasion by targeting the cytoskeleton network genes encoding twinfilin 1 (TWF1) and vimentin (VIM). 23224145 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group BEFREE Interestingly, ADT also induced high levels of vimentin expression in prostate cancer cell lines in vitro and in human prostate tumors in vivo. 21677876 2011
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group CTD_human Proteome analysis of human androgen-independent prostate cancer cell lines: variable metastatic potentials correlated with vimentin expression. 17566973 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group LHGDN Vimentin affects the mobility and invasiveness of prostate cancer cells. 18464297 2008
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group LHGDN Overexpression of vimentin: role in the invasive phenotype in an androgen-independent model of prostate cancer. 12727854 2003
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group BEFREE Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo. 19276168 2009
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group CTD_human The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. 24763052 2014
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group BEFREE Expression profiling and localization for EMT effectors, E-Cadherin, N-Cadherin, β-catenin and Vimentin was assessed in human prostate tumor specimens pre- and post-radiotherapy and correlated with biochemical recurrence. 29063620 2017
CUI: C0031149
Disease: Peritoneal Neoplasms
Peritoneal Neoplasms
0.300 Biomarker group CTD_human Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features. 22784439 2013
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases
0.300 Biomarker group CTD_human Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. 23075401 2013
Degenerative Diseases, Central Nervous System
0.300 Biomarker group CTD_human Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age. 16831193 2006
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders
0.300 Biomarker group CTD_human Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age. 16831193 2006
CUI: C0751733
Disease: Degenerative Diseases, Spinal Cord
Degenerative Diseases, Spinal Cord
0.300 Biomarker group CTD_human Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age. 16831193 2006